Searching 2.0

Searching for type 2 diabetes genes on chromosome 20.

Genome scans in families with type 2 diabetes identified a putative locus on chromosome 20q. For this study, linkage disequilibrium mapping was used in an effort to narrow a 7.3-Mb region in an Ashkenazi type 2 diabetic population. The region encompassed a 1-logarithm of odds (LOD) interval around the microsatellite marker D20S107, which gave a LOD score of >3 in linkage analysis of a combined ...

Lecture 2 : Searching Biological Database - August 20 , 2004

2.1.1 Biological Database Biological data are organized as a database of sequences. There are three types of biological sequences: Proteins, DNAs and RNAs. Large amounts of biological sequences are deposited in public databases. In recent years, the size of the biological database has doubled in every 15 or 16 months and in molecular biology, high-similarity search has become a basic operation ...

Savvy searching Citation searching

Citation searching has been available for decades, although in a limited form. This article discusses the advantages and limitations of searching by cited references, and also some alternatives in searching for cited references, before presenting a case study involving citation searching in full-text indexes.

Range Searching Range Searching

Some New Properties of the Searching Probability

Consider search designs for searching one nonzero 2- or 3-factor interaction under the search linear model. In the noisy case, search probability is given by Shirakura et al. (Ann. Statist. 24(6) (1996) 2560). In this paper some new properties of the searching probability are presented. New properties of the search probability enable us to compare designs, which depend on an unknown parameter ?...